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Barbara J. Mann, Ph.D.

Barbara J. Mann, Ph.D.Dr. Barbara Mann is an Associate Professor of Internal Medicine in the Division of Infectious Diseases and the Department of Microbiology at UVA. She and Dr. William Petri won the 2003 Edlich-Henderson Inventor of the Year Award awarded by the University of Virginia Patent Foundation for developing a rapid and specific diagnostic test for Entamoeba histolytica.  This test allows for the detection of E. histolytica from other commensal parasites and enables health care workers to treat children and adults suffering from diarrhea and dysentery by identifying the infecting agent.

Dr. Mann received undergraduate degree from Michigan State University, and her PhD in Microbiology from UVA.  She did a post-doctoral fellowship in fungal genetics at the University of Wisconsin.

Research Interests
Dr. Mann's research interest focuses on the initial interactions between a pathogen and its host. She studies adherence and invasion mechanisms and protective vaccines for two pathogens, the human parasite E. histolytica and the bacteria Francisella tularensis. Both of these organisms have been designated select agents of biological warfare and targeted for studies in bio-defense.

Dr. Mann's recent publications include "The genome of the protist parasite Entamoeba histolytica." Nature 433:865-8,  2004,  "Proteomic analysis of phagocytosis in the enteric protozoan  parasite Entamoeba  histolytica."  Eukaryotic Cell 4(4):827-31, 2005, and "Proteomic analysis of Gal/GalNAc Lectin associated proteins  in E.  histolytica"   Exp. Parasitol 110:220-225, 2005.  PubMed Listings for Dr. Barbara Mann